Honeysuckle makes a beautiful ground cover in many locations. Its light green leaves and delicate flowers add charm and beauty to gardens and woodlands. The problem is, many species of honeysuckle have become invasive. Honeysuckle chokes out other plants, takes over woodland areas and often runs wild in otherwise well-tended gardens. In such cases you must treat honeysuckle as a weed and take steps to kill it.
Pull up by hand as many honeysuckle plants as possible in early spring when the ground is soft and the roots of the honeysuckle are close to the surface. Bag and discard or, where permitted, burn all the plants you've pulled up. Remove even the smallest sprouts. Wear gloves for this job to avoid possible damage to your hands.
Use loppers and/or a chainsaw to cut back plants you couldn't pull out by hand. Discard or burn the honeysuckle.
Spray Roundup or a similar glyphosate-based herbicide on all remaining plants and stems. Do this immediately after cutting, before the cuts have a chance to dry out and heal over. If necessary to protect other plants, use a paintbrush to apply Roundup on the cut ends of the honeysuckle.
Wait two weeks for the honeysuckle treated with Roundup to die. Use gloves and shovels to dig up and remove as many dead plants as possible. Discard the dead honeysuckle or burn it. Do not bury it. You don't want it to grow back.
Reapply Roundup or similar herbicide to any new growth you see in late summer or early fall when plants are most susceptible to Roundup-type products. If spraying would endanger other plants, use a paintbrush to apply Roundup to surviving honeysuckle leaves. Be thorough. Apply Roundup to each and every plant.
Check the area again in the spring and repeat Step 1 if necessary, although by this time your problem should be almost solved.