Till the planting site to remove vegetation. Mix balanced commercial fertilizer with the loosened soil at the rate recommended on the package instructions.
Create raised beds using a garden hoe. Leave a space of approximately 27 to 40 inches between each bed.
Water the beds until the soil feels very moist just before planting. Sow the seeds approximately 3/4 to 1 1/2 inches deep. Plant 25 to 35 seeds per foot of garden space.
Avoid watering again until the seeds have sprouted to prevent the surface of the soil from crusting, which makes it difficult for the small seeds to emerge. Sesame is very tolerant of drought and should only be watered during extremely dry conditions.
Cultivate the soil around the plants shallowly with a garden hoe to remove weeds.
Harvest when the seed pods are dry but before they crack open.