How to Mix Glyphosate


To kill perennial weeds, you need a product called glyphosate. Glyphosate, N-(phosphonomethyl) glycine, can be purchased by itself or as an active ingredient in many name-brand herbicides. As with all chemicals, it is important that you fully read the product label and adhere to all safety recommendations before you mix the glyphosate with water to apply it to your weeds. This will also ensure that your weeds are treated correctly so you can get the best results from the herbicide.

Step 1

Put on a long-sleeved shirt, long pants, chemical-resistant gloves, goggles and a face mask. This is necessary to protect you from eye damage, skin irritation and respiratory distress that could occur if the chemical comes in contact with your body.

Step 2

Pour 13 oz. of glyphosate into a backpack sprayer.

Step 3

Add 1 gallon of water to the glyphosate in the backpack sprayer.

Step 4

Put the lid on the backpack sprayer, and shake the sprayer to combine the two ingredients. You now have enough glyphosate to cover 400 square feet. If you need to cover a bigger space, multiply the ingredients.

Step 5

Aim the backpack sprayer at the leaves of the weeds you want to kill. The chemical is absorbed through the leaves, not through the roots. Spray until all of the weeds are soaked.

Tips and Warnings

  • If you encounter a medical emergency during the use of this product, call 1-800-308-5391.

Things You'll Need

  • Long-sleeved shirt
  • Long pants
  • Chemical-resistant gloves
  • Goggles
  • Face mask
  • 13 oz. glyphosate
  • 1 gallon water
  • Backpack sprayer


  • Quali-Pro: Glyphosate TO Product Label
Keywords: killing weeds, mixing glyphosate, using glyphosate

About this Author

Alicia Bodine has been a professional writer for six years. She has produced thousands of articles for online publications such as Demand Studios, Bright Hub, Associated Content and WiseGeek. Bodine is also the current cooking guru for LifeTips. She has received awards for being a top content producer.