The scientific name for muscadines is Vitis rotundifolia. The muscadine is a vine that produces grapes. Like many other types of vegetation, muscadines are susceptible to aphids. Aphids are tiny insects with soft bodies. They like to suck out the juices of the leaves of the vines, causing the vines to die off. Without healthy vines, you cannot produce healthy grapes. Getting aphids off your muscadine vines isn't hard if you know what to do.
Spray the aphids off your muscadine vine with a hose that has the ability to produce a strong spray. Make sure you aim the hose underneath the leaves. If you have a small infestation, a few mornings of this should do the trick.
Fill your backpack sprayer with water and add a few tablespoons of dish soap. This creates a homemade insecticidal soap that can kill any aphids on your muscadine vines.
Spray the muscadine vine leaves with the insecticidal soap. Again, make sure you get underneath the leaves. This is where most aphids hang out. This will take care of a moderate infestation of aphids.
Mix a chemical insecticide that contains the ingredient malathion with water based on the product label directions. Mississippi State University recommends the use of malathion when aphids or spider mites are present on muscadine vines. This solution is only for severe infestations of aphids. You should try to avoid using chemicals on any vines that produce grapes, since you will be consuming those grapes later on.
Spray the chemical insecticide on the muscadine vines with the backpack sprayer the same way you did with your homemade insecticide. This will kill all of your aphids.