How to Use Glyphosate Herbicides


Glyphosate is a systemic, non-selective, broad-spectrum herbicide that provides an alternative to killing unwanted grasses, weeds and several plants by hand. Not only does it reduce time and intensity of labor involved, it is effective and eradicates the plant along with the roots completely without leaching into the soil. Herbicides such as Pondmaster, Rodeo and Roundup contain glyphosate and are favored by gardeners. A plant that absorbs glyphosate herbicides stops producing vital amino acids necessary for its growth. Although these herbicides are relatively safe for humans and pets, knowing how to use them properly is essential.

Step 1

Wear rubber gloves, protective eyeglasses, face mask, long-sleeved shirt, full pants and boots when using glyphosate herbicides to prevent the possibility of an eye or skin irritation.

Step 2

Read manufacturers instructions on your specific glyphosate herbicide product to determine whether you should add water to dilute the concentrate or use the solution full strength.

Step 3

Pour it directly on unwanted plants that are actively growing. You can also pour it over a sponge and squeeze out excess directly over the plant, or into a spray bottle and mist the unwanted plant. Make sure the plant comes into direct contact with the glyphosate herbicide so it penetrates the soft tissue in the stalk to prevent the synthesis of amino acids, thus killing it in days or weeks.

Step 4

Repeat the glyphosate herbicide application over any unwanted plant it did not kill after a month to 40 days.

Step 5

Remove your gloves, facemask and clothing after using the herbicide and put them in the wash. Take a shower and wear a clean change of clothes to prevent any contact with your eyes or nose, or with children or pets.

Tips and Warnings

  • Cover any plants near the unwanted ones with a tarp to prevent the glyphosate herbicide from accidentally dropping over them. Glyphosate herbicide is very strong and kills any plant it comes in contact with. Always put the glyphosate herbicide in a safe place out of the reach of children so they cannot access it easily. Do not cultivate the soil for two to three weeks after applying glyphosate herbicide there.

Things You'll Need

  • Rubber gloves
  • Safety eyeglasses
  • Face mask
  • Long-sleeved shirt
  • Pants
  • Boots
  • Glyphosate-based herbicide
  • Sponge
  • Spray bottle


  • Pan-UK: Glyphosate Factsheet
  • Extoxnet: Glyphosate
  • Pest Products: Roundup Herbicides
Keywords: weed killer, glyphosate herbicide, using glyphosate herbicides

About this Author

Tanya Khan is a freelance author and consultant, having written hundreds of thousands of words for various online and print sources. She has an MBA in Marketing but her passion lies in giving her words wings.